C .... Number of point mutations at the sequence level which caused the shape transition.
D .... Hamming distance between the current shape on the path and the target. (That's the number of positions in which two shapes - represented as in column G - differ.)
E .... total number of instances of shape i-1 at the time shape i was generated. (The average number of sequences sustainable in the reactor is 1000.) This number gives an indication of whether the ancestor shape was a dominant one.
F .... number of alternative ancestor shapes of shape i. (Shape i may have been present in the reactor on and off. Thus it may have been "rediscovered" several times. Column E gives the total number of different ancestor shapes which innovated the reactor with shape i over the entire history of the simulation.)
G .... shape. The shape is represented in a
"balanced parentheses" notation, in which a dot indicates an unpaired
position and a matching pair of parentheses stands for a base
pair. For example in ..(((((...))).)) the red pair of matching parentheses
represents a base pair between positions 4 and 15 in the sequence.
Click on the number in column A to see a graphical representation of
the secondary structure.
Colors have the same meaning as in the shape path plate (see the corresponding readme).