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Signalling architectures can prevent cancer evolution (2020)
L. Oña, M. Lachmann
Scientific reports 10(1)
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cancer , Cooperative behavior ,test
Effects of COVID-19 vaccination timing and risk prioritization on mortality rates, United States (2021)
X. Wang, Z. Du, K.E. Johnson, R.F. Pasco, S.J. Fox, M. Lachmann, J.S. McLellan, L.A. Meyers
Emerging Infectious Diseases 27(7)
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COVID-19
Cost-effective proactive testing strategies during COVID-19 mass vaccination: A modelling study (2022)
Z. Du, L. Wang, Y. Bai, X. Wang, A. Pandey, M.C. Fitzpatrick, M. Chinazzi, A.P. y Piontti, N. Hupert, M. Lachmann
The Lancet Regional Health-Americas 8
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COVID-19
Natural Selection beyond Life? A Workshop Report (2021)
S. Charlat, A. Ariew, P. Bourrat, M. Ferreira Ruiz, T. Heams, P. Huneman, S. Krishna, M. Lachmann, N. Lartillot, L. Le Sergeant d’Hendecourt
Life 11(10)
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origin of life
Real-Time Projections of SARS-CoV-2 B. 1.1. 7 Variant in a University Setting, Texas, USA (2021)
K.E. Johnson, S. Woody, M. Lachmann, S.J. Fox, J. Klima, T.S. Hines, L.A. Meyers
Emerging infectious diseases 27(12)
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COVID-19
Real-time pandemic surveillance using hospital admissions and mobility data (2022)
S.J. Fox, M. Lachmann, M. Tec, R. Pasco, S. Woody, Z. Du, X. Wang, T.A. Ingle, E. Javan, M. Dahan
Proceedings of the National Academy of Sciences 119(7)
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COVID-19
Epidemiologic information discovery from open-access COVID-19 case reports via pretrained language model (2022)
Z. Wang, X.F. Liu, Z. Du, L. Wang, Y. Wu, P. Holme, M. Lachmann, H. Lin, Z.S. Wong, X. Xu
iScience 25(10)
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COVID-19
Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States (2022)
E.Y. Cramer, E.L. Ray, V.K. Lopez, J. Bracher, A. Brennen, A.J. Castro Rivadeneira, A. Gerding, T. Gneiting, K.H. House, Y. Huang
Proceedings of the National Academy of Sciences 119(15)
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COVID-19
The effectiveness of COVID-19 testing and contact tracing in a US city (2022)
X. Wang, Z. Du, E. James, S.J. Fox, M. Lachmann, L.A. Meyers, D. Bhavnani
Proceedings of the National Academy of Sciences 119(34)
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COVID-19
On the fitness of informative cues in complex environments (2021)
F. Mafessoni, M. Lachmann, C.S. Gokhale
Journal of Theoretical Biology 527
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Information
The experience of 2 independent schools with in‐person learning during the COVID‐19 pandemic (2021)
D.L. Gillespie, L.A. Meyers, M. Lachmann, S.C. Redd, J.M. Zenilman
Journal of School Health 91(5)
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COVID-19
Comparative cost-effectiveness of SARS-CoV-2 testing strategies in the USA: a modelling study (2021)
Z. Du, A. Pandey, Y. Bai, M.C. Fitzpatrick, M. Chinazzi, A.P. y Piontti, M. Lachmann, A. Vespignani, B.J. Cowling, A.P. Galvani
The Lancet Public Health 6(3)
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COVID-19
The complexity of understanding others as the evolutionary origin of empathy and emotional contagion (2019)
F. Mafessoni, M. Lachmann
Scientific Reports 9(1)
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What can Schrödinger’s cat say about 3D printers on Mars? (2019)
M. Lachmann, S. Walker
Aeon
origin of life
Epigenetic inheritance systems contribute to the evolution of a germline. (2016)
M. Lachmann, E. Libby
Philos Trans R Soc Lond B Biol Sci 371(1701)
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epigenetics , multicellularity
Human adaptation and population differentiation in the light of ancient genomes. (2016)
F.M. Key, Q. Fu, F. Romagné, M. Lachmann, A.M. Andrés
Nat Commun 7
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Ancient DNA
Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes. (2016)
R.B. Prasad, A. Lessmark, P. Almgren, ..., S. Pääbo, L. Koranyi, L. Groop
Diabetologia 59(8)
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Ancient DNA
Selective Strolls: Fixation and Extinction in Diploids Are Slower for Weakly Selected Mutations Than for Neutral Ones. (2015)
F. Mafessoni, M. Lachmann
Genetics 201(4)
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popgen
The complete genome sequence of a Neanderthal from the Altai Mountains (2014)
K. Prüfer, F. Racimo, N. Patterson, ..., D. Reich, J. Kelso, S. Pääbo
Nature 505(7481)
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Ancient DNA
Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans (2014)
E.E. Khrameeva, K. Bozek, L. He, ..., P. Giavalisco, M. Lachmann, P. Khaitovich
Nature Communications 5(1)
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Ancient DNA
When unreliable cues are good enough. (2013)
M.C. Donaldson-Matasci, C.T. Bergstrom, M. Lachmann
Am Nat 182(3)
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Information
The value of information in signals and cues (2013)
M. Lachmann
Animal communication theory
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Information
Great ape genetic diversity and population history (2013)
J. Prado-Martinez, P.H. Sudmant, J.M. Kidd, ..., M.F. Hammer, E.E. Eichler, T. Marques-Bonet
Nature 499(7459)
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popgen
On the role of resonance in drug failure under HIV treatment interruption (2013)
L. Oña, R.D. Kouyos, M. Lachmann, S. Bonhoeffer
Theoretical Biology and Medical Modelling 10(1)
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The bonobo genome compared with the chimpanzee and human genomes (2012)
K. Prüfer, K. Munch, I. Hellmann, ..., A.M. Andrés, J. Kelso, S. Pääbo
Nature 486(7404)
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Analysis of Human Accelerated DNA Regions Using Archaic Hominin Genomes (2012)
H.A. Burbano, R.E. Green, T. Maricic, ..., K.S. Pollard, M. Lachmann, S. Pääbo
PLOS ONE 7(3)
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'maskBAD' - a package to detect and remove Affymetrix probes with binding affinity differences (2012)
M. Dannemann, M. Lachmann, A. Lorenc
BMC Bioinformatics 13(1)
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methods , Evolution of differentiation
Inferring the History of Population Size Change from Genome-Wide SNP Data (2012)
C. Theunert, K. Tang, M. Lachmann, S. Hu, M. Stoneking
Molecular Biology and Evolution 29(12)
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popgen
The adaptive value of developmental plasticity in response to individually variable cues (2011)
M.C. Donaldson-Matasci, C.T. Bergstrom, M. Lachmann

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Information , plasticity
Ant aggression and evolutionary stability in plant–ant and plant–pollinator mutualistic interactions (2011)
L. Oña, M. Lachmann
Journal of Evolutionary Biology 24(3)
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ants , Cooperative behavior
Targeted investigation of the Neandertal genome by array-based sequence capture. (2010)
H.A. Burbano, E. Hodges, R.E. Green, ..., M. Lachmann, G.J. Hannon, S. Pääbo
Science 328(5979)
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Ancient DNA, neandertal
A draft sequence of the Neandertal genome. (2010)
R.E. Green, J. Krause, A.W. Briggs, ..., M. Lachmann, D.E. Reich, S. Pääbo
Science 328(5979)
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neandertal , Ancient DNA
The fitness value of information. (2010)
M.C. Donaldson-Matasci, C.T. Bergstrom, M. Lachmann
Oikos 119(2)
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Information
MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain (2010)
M. Somel, S. Guo, N. Fu, ..., R. Zeng, W. Chen, P. Khaitovich
Genome Research 20(9)
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heterochrony , Evolution of differentiation
The effects of probe binding affinity differences on gene expression measurements and how to deal with them. (2009)
M. Dannemann, A. Lorenc, I. Hellmann, P. Khaitovich, M. Lachmann
Bioinformatics (Oxford, England) 25(21)
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methods , gene expression
The Neandertal genome and ancient DNA authenticity. (2009)
R.E. Green, A.W. Briggs, J. Krause, ..., M. Siebauer, M. Lachmann, S. Pääbo
The EMBO journal 28(17)
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neandertal , Ancient DNA
Transcriptional neoteny in the human brain. (2009)
M. Somel, H. Franz, Z. Yan, ..., M. Lachmann, S. Pääbo, P. Khaitovich
Proceedings of the National Academy of Sciences 106(14)
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heterochrony , Evolution of differentiation
Linkage disequilibrium extends across putative selected sites in FOXP2. (2009)
S.E. Ptak, W. Enard, V. Wiebe, I. Hellmann, J. Krause, M. Lachmann, S. Pääbo
Molecular Biology and Evolution 26(10)
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popgen
The fitness value of information (2009)
M. Lachmann, M. Donaldson-Mataschi, C.T. Bergstrom

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Information
Phenotypic diversity as an adaptation to environmental uncertainty (2008)
M.C. Donaldson-Matasci, M. Lachmann, C.T. Bergstrom
Evolutionary Ecology Research 10(4)
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Information , plasticity
Human and chimpanzee gene expression differences replicated in mice fed different diets. (2008)
M. Somel, H. Creely, H. Franz, U. Mueller, M. Lachmann, P. Khaitovich, S. Pääbo
PLoS One 3(1)
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Evolution of differentiation
PatMaN: rapid alignment of short sequences to large databases (2008)
K. Prüfer, U. Stenzel, M. Dannemann, ..., R.E. Green, M. Lachmann, J. Kelso
Bioinformatics 24(13)
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Ancient DNA , methods
Building trust by wasting time (2008)
C.T. Bergstrom, B. Kerr, M. Lachmann
Moral markets: The critical role of values in the economy
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Cooperative behavior
The evolution of functionally referential meaning in a structured world. (2007)
M.C. Donaldson, M. Lachmann, C.T. Bergstrom
Journal of Theoretical Biology 246(2)
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Information
Patterns of damage in genomic DNA sequences from a Neandertal (2007)
A.W. Briggs, U. Stenzel, P.L.F. Johnson, ..., M.T. Ronan, M. Lachmann, S. Pääbo
Proceedings of the National Academy of Sciences 104(37)
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Ancient DNA, neandertal
FUNC: a package for detecting significant associations between gene sets and ontological annotations (2007)
K. Prüfer, B. Muetzel, H. Do, ..., S. Pääbo, M. Lachmann, W. Enard
BMC Bioinformatics 8(1)
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methods , Evolution of differentiation
Evolution of primate gene expression (2006)
P. Khaitovich, W. Enard, M. Lachmann, S. Pääbo
Nature Reviews Genetics 7(9)
Evolution of differentiation
Gene expression becomes heterogeneous with age (2006)
M. Somel, P. Khaitovich, S. Bahn, S. Pääbo, M. Lachmann
Current Biology 16(10)
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heterochrony , Evolution of differentiation
Positive selection on gene expression in the human brain (2006)
P. Khaitovich, K. Tang, H. Franz, ..., W. Enard, M. Lachmann, S. Pääbo
Current Biology 16(10)
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Evolution of differentiation
Evolution of primate gene expression (2006)
P. Khaitovich, W. Enard, M. Lachmann, S. Pääbo
Nature Reviews Genetics 7(9)
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Evolution of differentiation
Functionality of Intergenic Transcription: An Evolutionary Comparison (2006)
P. Khaitovich, J. Kelso, H. Franz, ..., R.E. Green, M. Lachmann, S. Pääbo
PLOS Genetics 2(10)
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Evolution of differentiation
Quasispecies made simple. (2005)
J.J. Bull, L.A. Meyers, M. Lachmann
PLoS Comput Biol 1(6)
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Information, popgen
Parallel Patterns of Evolution in the Genomes and Transcriptomes of Humans and Chimpanzees (2005)
P. Khaitovich, I. Hellmann, W. Enard, ..., G. Weiss, M. Lachmann, S. Pääbo
Science 309(5742)
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Evolution of differentiation
Evolution of Genetic Potential (2005)
L.A. Meyers, F.D. Ancel, M. Lachmann
PLOS Computational Biology 1(3)
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popgen
Shannon information and biological fitness (2004)
C.T. Bergstrom, M. Lachmann
Information Theory Workshop, 2004. IEEE
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Information
The disadvantage of combinatorial communication. (2004)
M. Lachmann, C.T. Bergstrom
Proceedings of the Royal Society of London. Series B: Biological Sciences 271(1555)
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signalling
The physical limits of communication or Why any sufficiently advanced technology is indistinguishable from noise (2004)
M. Lachmann, M.E.J. Newman, C. Moore
Am. J. Phys. 72(10)
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fun
A neutral model of transcriptome evolution. (2004)
P. Khaitovich, G. Weiss, M. Lachmann, ..., U. Wirkner, W. Ansorge, S. Pääbo
PLoS Biol 2(5)
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Evolution of differentiation
Regional Patterns of Gene Expression in Human and Chimpanzee Brains (2004)
P. Khaitovich, B. Muetzel, X. She, ..., K. Nieselt-Struwe, E.E. Eichler, S. Pääbo
Genome Research 14(8)
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Evolution of differentiation
Cooperation and Conflict in the evolution of genomes, cells, and multicellular organisms (2003)
M. Lachmann, N.W. Blackstone, D. Haig, ..., E. Szathmary, J.H. Werren, L. Wolpert
Genetic and cultural evolution of cooperation
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Cooperative behavior , multicellularity
The Red King effect: When the slowest runner wins the coevolutionary race (2003)
C.T. Bergstrom, M. Lachmann
Proceedings of the National Academy of Sciences 100(2)
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popgen
On the evolution of polygyny: a theoretical examination of the polygyny threshold model (2003)
S.E. Ptak, M. Lachmann
Behavioral Ecology 14(2)
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popgen
Separating equilibria in continuous signalling games (2002)
R.A. Johnstone, S.R.X. Dall, C.T. Bergstrom, S. Számadó, M. Lachmann
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 357(1427)
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signalling
Cost and conflict in animal signals and human language (2001)
M. Lachmann, S. Számadó, C.T. Bergstrom
Proceedings of the National Academy of Sciences 98(23)
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signalling
Alarm calls as costly signals of antipredator vigilance: the watchful babbler game (2001)
C.T. Bergstrom, M. Lachmann
Animal Behaviour 61(3)
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signalling
Role of begging and sibling competition in foraging strategies of nestlings (2001)
M.A. Rodrı́guez-Gironés, M. Enquist, M. Lachmann
Animal Behaviour 61(4)
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signalling
On the advantages of information sharing (2000)
M. Lachmann, G. Sella, E. Jablonka
Proceedings of the Royal Society of London. Series B: Biological Sciences 267(1450)
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Information , multicellularity
On the dynamic persistence of cooperation: how lower individual fitness induces higher survivability. (2000)
G. Sella, M. Lachmann
J Theor Biol 206(4)
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Cooperative behavior , multicellularity
Who Wins Domineering on Rectangular Boards? (2000)
M. Lachmann, C. Moore, I. Rapaport
arXiv:math/0006066
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fun
Adopting adoption (1998)
E. Avital, E. Jablonka, M. Lachmann
Animal Behaviour 55(6)
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epigenetics
Signaling among relatives. III. Talk is cheap (1998)
C.T. Bergstrom, M. Lachmann
Proceedings of the National Academy of Sciences 95(9)
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signalling
Signalling among Relatives: II. Beyond the Tower of Babel (1998)
M. Lachmann, C.T. Bergstrom
Theoretical Population Biology 54(2)
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signalling
Signalling among relatives. I. Is costly signalling too costly? (1997)
C.T. Bergstrom, M. Lachmann
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 352(1353)
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signalling
The Inheritance of Phenotypes: an Adaptation to Fluctuating Environments (1996)
M. Lachmann, E. Jablonka
Journal of Theoretical Biology 181(1)
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Information , epigenetics
The computationally complete ant colony: Global coordination in a system with no hierarchy (1995)
M. Lachmann, G. Sella
European Conference on Artificial Life
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ants , Cooperative behavior
The alternative fitness sets which preserve allele trajectories: a general treatment. (1994)
M. Lachmann-Tarkhanov, S. Sarkar
Genetics 138(4)
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popgen
Evidence, mechanisms and models for the inheritance of acquired characters (1992)
E. Jablonka, M. Lachmann, M.J. Lamb
Journal of Theoretical Biology 158(2)
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epigenetics
Origins of Evolution (1991)
M. Lachmann

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origin of life


	Michael Lachmann




	Research Areas
	Multicellularity Ants Costly signalling Language Origin of life Misc

	Publications
	Google scholar


	Teaching
	R-Course 2004 R-Course 2006 R-Course 2010 Group Selection Course